Digoxin, derived from the leaves of plants digitalis (leaves used as medicine to strengthen the heart). Digoxin helps make the heart beat stronger and with more regular rhythm.
Indications:
To treat congestive heart failure, is also used to treat atrial fibrillation, heart rhythm disturbances in the atria (the upper porch of the heart that allow blood to flow to the heart).
Dosage:
62.5-250 mcg orally (by mouth), 1 times daily
Side Effects:
1. Side effects are usually due to poisoning or overdose of Digoxin and Digoxin is usually well received if given in accordance with the recommended dose for congestive heart failure (CHF).
2. Digoxin poisoning: Effects of GI (N/V, anorexia, diarrhea, abdominal pain) is usually the first signs of toxicity Digoxin; Other signs of toxicity Digoxin: CNS effects (headache, fatigue, pain in the face, weakness, dizziness, mental confusion), disturbance of vision (blurred vision, impaired color); toxin can cause serious CV effects (worsening heart failure (HF), arrhythmias, conduction were found.)
3. Hypokalemia can affect a person on Digoxin poisoning.
4. Hypersensitivity reactions are rather rare.
Special Instructions:
1. Digoxin low dose (62.5 mcg / day or 125 mcg every other day) should be used in older people, patients with impaired renal function or patients with low body mass (lean).
2. Loading dose is not required in patients with congestive heart failure (CHF).
3. Avoid in patients with obstructive cardiomyopathy unless there were acute heart failure, in patients with syndrome Wolff-Parkinson-White (WPW) may not be used for ventricular arrhythmias.
4. Use with caution in cases of partial heart barrier, impaired trunk sinus, acute myocarditis, MI (myocardial infarction) acute, severe heart failure, acute pulmonary disease, in patients undergoing cardioversion (consider stopping cardioversion within 1-2 days before procedure done) and with other drugs that can suppress the function of sinus and AV nodal function (eg, Amiodarone or beta-blockers).
5. Hypokalemia, hyperkalemia, hipomagnesemia, hypoxia, and hyperthyroidism can affect sensitivity to digoxin.
6. Digoxin level supervision is only required if the alleged poisoning.
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